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KMID : 0360220080490020230
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Journal of the Korean Ophthalmological Society
2008 Volume.49 No. 2 p.230 ~ p.237
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Two-year Endothalial Changes after Iris Fixed Phakic Intraocular Lens Implantation in Korean
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Choi Woo-Seok
Choi Bong-Joon
Her Jun
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Abstract
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Purpose : To investigate quantitative and morphometric endothelial changes in phakic eyes implanted with an
iris-fixed phakic intraocular lens in Korean patients.
Methods : We prospectively examined the endothelial cell density (ECD), ECD loss (ECL), coefficient
variations (CV), and frequency of Hexagons (6A) in 46 phakic eyes implanted with an iris-fixed phakic
intraocular lens. The effect of anterior chamber depth (ACD) and diopter of iris-fixed phakic intraocular lens
on ECD was statistically analyzed.
Results : Preoperative mean ECD was 2923±257 cells/mm2. ECL at postoperative 1, 3, 6, 12, and 24
monthswas 0.71%, 0.88%, 0.70%, 0.64%, and 2.34%. It was significant only in the month 24 results. The
mean CV value at the same time was 0.343, 0.342, 0.334, 0.329, 0.326, and 0.338. The change was
significant at the 12th month. The mean 6A value at the same time was 58.2%, 57.8%, 59.7%, 59.6%, 60.1%,
and 58.8%. There was no significant change in 6A value. Preoperative ACD and diopter of iris-fixed phakic
intraocular lens didn’t affect the ECD change.
Conclusion : This two-year follow-up study of changes in endothelial cells after implantation iris-fixated
phakic intraocular lens showed statistically significant decreases in the cells, which is not very significant
considering the physiologic reduction rate of the cells. Thses decreases showed a tendency to be stabilized
with recovery of morphological changes. Further long-term follow-up is needed to determine its long-lasting
effect.
J Korean Ophthalmol Soc 49(2):230-237, 2008
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KEYWORD
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Endothelial cell density, Iris fixed phakic intraocular Lens, Morphometric change
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